Ne t\u00eb gjith\u00eb e dim\u00eb se planeti po testohet nga nj\u00eb pandemi e papar\u00eb e njohur si COVID-19 e shkaktuar nga virusi SARS-CoV-2, nj\u00eb virus ARN q\u00eb ka vrar\u00eb miliona deri m\u00eb tani.
Zgjidhja e vetme masive p\u00ebr momentin \u00ebsht\u00eb vaksinimi, por qarkullimi i vaksinave \u00ebsht\u00eb shoq\u00ebruar me nj\u00eb shp\u00ebrthim t\u00eb l\u00ebvizjes kund\u00ebr vaksinimit q\u00eb po pengon njer\u00ebzit t\u00eb vaksinohen.<\/p>\n\n\n\n
\u00cbsht\u00eb nj\u00eb reagim q\u00eb bazohet m\u00eb shum\u00eb n\u00eb frik\u00ebn dhe adoptimin e teorive q\u00eb nuk jan\u00eb provuar, por q\u00eb ting\u00ebllojn\u00eb mbres\u00ebl\u00ebn\u00ebse dhe t\u00eb frikshme si dragonjt\u00eb dhe shtrigat e p\u00ebrrallave. Nj\u00eb shqet\u00ebsim i till\u00eb \u00ebsht\u00eb mund\u00ebsia e ndikimit negativ n\u00eb pjellorin\u00eb mashkullore, shpjegon Z. Vassilis Protogerou, Kirurg Urolog-Androlog Profesor i Asociuar i Shkoll\u00ebs Mjek\u00ebsore t\u00eb Athin\u00ebs Drejtor i Klinik\u00ebs s\u00eb 5-t\u00eb Urologjike Metropolitan General.<\/p>\n\n\n\n
SARS-CoV-2 dhe pjelloria mashkullore<\/p>\n\n\n\n
Virusi, p\u00ebrmes nj\u00eb proteine (S-spike) q\u00eb ka, hyn n\u00eb qeliza pasi lidhet s\u00eb pari me nj\u00eb protein\u00eb \/ receptor n\u00eb qelizat njer\u00ebzore, ACE2. Problemi \u00ebsht\u00eb se sistemi riprodhues mashkullor ka nj\u00eb num\u00ebr t\u00eb madh t\u00eb receptor\u00ebve ACE2 gj\u00eb q\u00eb e b\u00ebn at\u00eb t\u00eb preksh\u00ebm ndaj virusit. N\u00eb t\u00eb v\u00ebrtet\u00eb, shum\u00eb studime kan\u00eb konfirmuar se burrat e infektuar me virusin kan\u00eb zhvilluar orkit, epididymit dhe prostatit, nd\u00ebrsa analiza histologjike e k\u00ebtyre zonave tregoi d\u00ebme t\u00eb konsiderueshme.<\/p>\n\n\n\n
N\u00eb pacient\u00ebt q\u00eb u sh\u00ebruan, u zbuluan \u00e7rregullime t\u00eb cil\u00ebsis\u00eb s\u00eb sperm\u00ebs t\u00eb cilat mund t\u00eb jen\u00eb p\u00ebr shkak t\u00eb shkaqeve t\u00eb tjera p\u00ebrve\u00e7 d\u00ebmtimit t\u00eb sistemit gjenital pasi ka d\u00ebshmi t\u00eb d\u00ebmtimit t\u00eb virusit n\u00eb tru, duke rezultuar n\u00eb prishje t\u00eb boshtit hipotalamus-hipofiz\u00eb-testikul q\u00eb rregullon spermatogjenez\u00ebn.<\/p>\n\n\n\n
Gjithashtu, zhvillohet stresi oksidativ i cili shkat\u00ebrron sperm\u00ebn dhe gjithashtu prish hormonet q\u00eb lidhen me prodhimin e sperm\u00ebs. K\u00ebta jan\u00eb t\u00eb gjith\u00eb element\u00eb q\u00eb shkaktojn\u00eb shqet\u00ebsim t\u00eb madh p\u00ebr rezultatin p\u00ebrfundimtar t\u00eb pjelloris\u00eb mashkullore n\u00eb nj\u00eb njeri t\u00eb infektuar me virus.<\/p>\n\n\n\n
Vaksinat p\u00ebr SARS-CoV-2<\/p>\n\n\n\n
Vaksinat aktualisht t\u00eb disponueshme jan\u00eb nga Pfizer, Moderna, AstraZeneca dhe Janssen. Nga k\u00ebto, Pfizer (BNT162b2) dhe Moderna (mRNA 1273) jan\u00eb ARNi. Me pak fjal\u00eb, k\u00ebto vaksina jan\u00eb nj\u00eb teknologji q\u00eb daton n\u00eb vitet 1990 dhe bazohen n\u00eb faktin se n\u00eb vend t\u00eb nj\u00eb virusi, ata futin n\u00eb trup gati kodimin q\u00eb trupi yn\u00eb do t\u00eb b\u00ebnte n\u00eb form\u00ebn e ARNi. ARNi sintetizon protein\u00ebn S t\u00eb virusit dhe k\u00ebshtu aktivizon mbrojtjen ton\u00eb. Vaksina Johnson (Ad26.COV2.S) \u00ebsht\u00eb nj\u00eb teknologji e fundit e viteve 1970 dhe p\u00ebrdor adenovirusin 26 t\u00eb \u00e7aktivizuar si nj\u00eb vektor q\u00eb p\u00ebrmban informacion n\u00eb lidhje me sintez\u00ebn e proteinave S n\u00eb gjenomin e tij. AstraZeneca (AZD1222), e nj\u00ebjta teknologji si Johnson, p\u00ebrdor nj\u00eb virus tjet\u00ebr si vektor q\u00eb gjithashtu p\u00ebrmban informacionin e proteinave S.<\/p>\n\n\n\n
Kur virusi i v\u00ebrtet\u00eb t\u00eb hyj\u00eb n\u00eb trupin ton\u00eb, proteina \/ thumba S do t\u00eb shkat\u00ebrrohet dhe lidhja e saj me qelizat tona do t\u00eb parandalohet dhe rrjedhimisht do t\u00eb vdes\u00eb pasi nga natyra viruset nuk jetojn\u00eb jasht\u00eb qelizave.<\/p>\n\n\n\n
Vaksinat dhe pjelloria<\/p>\n\n\n\n
Ajo q\u00eb dim\u00eb deri m\u00eb tani p\u00ebr vaksinat: njohurit\u00eb tona vijn\u00eb nga studimet e b\u00ebra mbi Pfizer dhe Moderna n\u00eb SHBA dhe Izrael. N\u00eb nj\u00eb studim q\u00eb p\u00ebrfshin t\u00eb dy vaksinat, cil\u00ebsia e sperm\u00ebs u kontrollua para dhe pas p\u00ebrfundimit t\u00eb vaksinimit dhe u zbulua se nuk kishte ndonj\u00eb ndryshim n\u00eb cil\u00ebsin\u00eb e sperm\u00ebs.<\/p>\n\n\n\n
P\u00ebrkundrazi, pati nj\u00eb rritje t\u00eb numrit t\u00eb spermatozoideve dhe \u00ebsht\u00eb interesante se nga 8 burrat q\u00eb kishin nj\u00eb num\u00ebr patologjik para vaksinimit, 7 u kthyen n\u00eb normale. Kjo nuk mund t\u00eb shpjegohet dhe as nuk konsiderohet statistikisht dometh\u00ebn\u00ebse rritja e numrit t\u00eb spermatozoideve n\u00eb t\u00ebr\u00ebsi. Sidoqoft\u00eb, \u00ebsht\u00eb tregues i efektit jo-negativ t\u00eb vaksin\u00ebs n\u00eb pjellorin\u00eb.
N\u00eb nj\u00eb studim tjet\u00ebr vet\u00ebm p\u00ebr Pfizer, t\u00eb nj\u00ebjtat rezultate u gjet\u00ebn: jo nj\u00eb r\u00ebnie, por nj\u00eb rritje (jo statistikisht e r\u00ebnd\u00ebsishme) n\u00eb numrin e sperm\u00ebs dhe nj\u00eb p\u00ebrmir\u00ebsim n\u00eb numrin e burrave q\u00eb kishin nj\u00eb num\u00ebr jonormal t\u00eb sperm\u00ebs para vaksinimit.<\/p>\n\n\n\n
Gjithashtu, n\u00eb nj\u00eb studim t\u00eb kryer n\u00eb nj\u00eb qend\u00ebr t\u00eb fekondimit in vitro, u studiua efekti q\u00eb vaksinimi Pfizer mund t\u00eb kishte te t\u00eb dy \u00e7iftet. U zbulua se nuk kishte asnj\u00eb efekt n\u00eb materialin gjenetik t\u00eb gruas t\u00eb marr\u00eb p\u00ebr fekondim in vitro dhe burrat gjithashtu treguan nj\u00eb rritje n\u00eb numrin e sperm\u00ebs (jo statistikisht e r\u00ebnd\u00ebsishme). Ve\u00e7an\u00ebrisht, nd\u00ebrsa \u00e7iftet para vaksin\u00ebs kishin d\u00ebshtuar n\u00eb IVF, pas vaksinimit 3 nga 36 \u00e7iftet kishin IVF t\u00eb suksessh\u00ebm.
Edhe pse studimet jan\u00eb ende t\u00eb vogla n\u00eb madh\u00ebsi dhe nuk mbulojn\u00eb t\u00eb gjitha vaksinat, fotografia \u00ebsht\u00eb se vaksinat nuk d\u00ebmtojn\u00eb pjellorin\u00eb mashkullore. Kjo \u00ebsht\u00eb arsyeja pse Shoq\u00ebria p\u00ebr Riprodhimin dhe Urologjin\u00eb Mashkullore (SMRU) dhe Shoq\u00ebria p\u00ebr Studimin e Riprodhimit Mashkullor (SSMR) rekomanduan n\u00eb janar 2021 q\u00eb burrat q\u00eb duhet t\u00eb vaksinohen duhet t\u00eb vazhdojn\u00eb normalisht pa hezitim p\u00ebr pjellorin\u00eb e tyre.<\/p>\n\n\n\n
Prandaj, burrat q\u00eb duhet t\u00eb vaksinohen mund t\u00eb vaksinohen sepse vaksinat me t\u00eb dh\u00ebnat e deritanishme jan\u00eb t\u00eb sigurta dhe jan\u00eb heronjt\u00eb modern\u00eb q\u00eb do t\u00eb luftojn\u00eb bestytnit\u00eb, dragonjt\u00eb dhe shtrigat.<\/p>\n","protected":false},"excerpt":{"rendered":"
Ne t\u00eb gjith\u00eb e dim\u00eb se planeti po testohet nga nj\u00eb pandemi e papar\u00eb e njohur si COVID-19 e shkaktuar nga virusi SARS-CoV-2, nj\u00eb virus ARN q\u00eb ka vrar\u00eb miliona…<\/p>\n","protected":false},"author":1,"featured_media":6845,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2],"tags":[],"class_list":["post-6844","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lajme-nga-vendi"],"_links":{"self":[{"href":"https:\/\/parleralbania.com\/site\/wp-json\/wp\/v2\/posts\/6844","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/parleralbania.com\/site\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/parleralbania.com\/site\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/parleralbania.com\/site\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/parleralbania.com\/site\/wp-json\/wp\/v2\/comments?post=6844"}],"version-history":[{"count":1,"href":"https:\/\/parleralbania.com\/site\/wp-json\/wp\/v2\/posts\/6844\/revisions"}],"predecessor-version":[{"id":6846,"href":"https:\/\/parleralbania.com\/site\/wp-json\/wp\/v2\/posts\/6844\/revisions\/6846"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/parleralbania.com\/site\/wp-json\/wp\/v2\/media\/6845"}],"wp:attachment":[{"href":"https:\/\/parleralbania.com\/site\/wp-json\/wp\/v2\/media?parent=6844"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/parleralbania.com\/site\/wp-json\/wp\/v2\/categories?post=6844"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/parleralbania.com\/site\/wp-json\/wp\/v2\/tags?post=6844"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}